| Date | Transaction | |||
| 9/25/08 | RHP Todd Jones announced his retirement. | |||
| 9/17/08 | Purchased the contract of RHP Freddy Garcia from Triple-A Toledo. Transferred RHP Joel Zumaya from the 15-day to the 60-day disabled list. | |||
| 9/2/08 | Recalled RHP Chris Lambert and LHP Clay Rapada from Triple-A Toledo. Purchased the contracts of INF Mike Hessman and C Dusty Ryan from Toledo. Transferred RHP Jeremy Bonderman and C Vance Wilson from the 15-day to the 60-day disabled list. | |||
| 9/1/08 | Recalled LHP Dontrelle Willis and RHP Freddy Dolsi from Triple-A Toledo. | |||
